More than 1.4 million Palestinians were sheltering in Rafah, Gaza's southernmost city near the Egyptian border, before Israel launched an offensive on May 7.
Most of them had fled to Rafah from other parts of Gaza, which were bombed by the Israeli regime.
Meanwhile, at least 12 people, including women and children, were killed in overnight attacks by Israeli forces on homes in southern Gaza's Khan Younis and Rafah cities, according to the Wafa news agency.
Three children were among 10 people killed when two homes were destroyed in Israeli attacks on a neighborhood in eastern Khan Younis.
A separate attack on the home of the Abu Khater family in Khan Younis left two people dead and many wounded, Wafa reports.
In Rafah, an attack on the Abu Ubaid family home in the Saudi neighborhood and the Oreiba area resulted in casualties, but the number of dead and injured is not yet known.
The Israeli military claimed to have struck 50 targets across the Gaza Strip in the last 24 hours, killing numerous civilians, including six women and children in an air attack on the Bureij refugee camp.
At least 36,439 Palestinians have been killed and 82,627 wounded in Israeli onslaught on Gaza since October 7.